Application
staining metabotropic Glutamate Receptor 6/7 in human brain by Immunohistochemistry (FFPE-sections).Application
Human Brain stained with anti-GluR6/7 antibody| Product Name | GPRC1F + GPRC1G antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to metabotropic Glutamate Receptor 6+7Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR17, NMDA13, KAI2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron. |
| Immunogen | Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PIPWB |
| IHC-P: Use at a dilution of 1/100 for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate, pH 6.0 for 10 min followed by cooling at RT for 20 min. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 105 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseMonkeyRat |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CSNB1B FLJ40498 DKFZp686H1993 GLUR7 GPRC1F GPRC1G MGLUR6 MGLU7 mGlu6 MGLUR7 |
|---|---|
| Target | GPRC1F + GPRC1G |
| Cellular Localization | Integral membrane protein |
Application
staining metabotropic Glutamate Receptor 6/7 in human brain by Immunohistochemistry (FFPE-sections).
Application
Human Brain stained with anti-GluR6/7 antibody| Positive Control | Brain lysate |
|---|---|
| Application Notes | IHC-P: Use at a dilution of 1/100 for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate, pH 6.0 for 10 min followed by cooling at RT for 20 min. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 105 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide |
