Application
GREM2 antibody [C1C3] detects GREM2 protein at cytoplasm on human placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. GREM2 antibody [C1C3] dilution: 1:100.Application
Whole cell extract (30 µg) was separated by 15% SDS-PAGE, and the membrane was blotted with GREM2 antibody [C1C3] diluted at 1:500.| Product Name | GREM2 antibody [C1C3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to GREM2 (gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis))This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GREM2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Rhesus MonkeyMouse (100%), Rat (100%), Rhesus Monkey (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CKTSF1B2 antibody, DAND3 antibody, PRDC antibody, GREM2 antibody, DAN domain family member 3 antibody, "cysteine knot superfamily 1, BMP antagonist 2 antibody", protein related to DAN and cerberus antibody, "gremlin 2, cysteine knot superfamily, homolog an |
|---|---|
| Target | GREM2 |
| Molecular Weight(MW) | 19 kDa (note) |
| Cellular Localization | Secreted |
Application
GREM2 antibody [C1C3] detects GREM2 protein at cytoplasm on human placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. GREM2 antibody [C1C3] dilution: 1:100.
Application
Whole cell extract (30 µg) was separated by 15% SDS-PAGE, and the membrane was blotted with GREM2 antibody [C1C3] diluted at 1:500.| Positive Control | A549 , IMR32 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
