Application
Sample (30μg whole cell lysate) A:MOLT4 7.5% SDS PAGE diluted at 1:1000Application
GRK2 antibody [N3C3-2] detects GRK2 protein at cytosol on mouse brain stem by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain stem. GRK2 antibody [N3C3-2] dilution: 1:500.| Product Name | GRK2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to GRK2 (adrenergic, beta, receptor kinase 1)The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human GRK2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | HumanMouse |
| Predicted Reactivity | Rat, Pig, BovineRat (98%), Pig (99%), Bovine (99%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BARK1 antibody BETA-ARK1 antibody FLJ16718 antibody GRK2 antibody ADRBK1 antibody G-protein coupled receptor kinase 2 antibody beta-ARK-1 antibody beta-adrenergic receptor kinase 1 antibody "adrenergic beta receptor kinase 1 antibody" |
|---|---|
| Target | GRK 2 |
| Molecular Weight(MW) | 80 kDa (note) (2) |
Application
Sample (30μg whole cell lysate) A:MOLT4 7.5% SDS PAGE diluted at 1:1000
Application
GRK2 antibody [N3C3-2] detects GRK2 protein at cytosol on mouse brain stem by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain stem. GRK2 antibody [N3C3-2] dilution: 1:500.| Positive Control | H1299 , Molt-4 , Raji |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
