Application
Western blot of rat cortex lysate showing phospho-specific immunolabeling of the ~46k GSK3p protein phosphorylated at Ser 9 using Glycogen synthase kinase 3 B (GSK3B) (phospho Ser9) antibody .| Product Name | GSK3 beta (phospho Ser9) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to GSK3 beta (phospho Ser9)Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1. |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser9 conjugated to KLH |
| Modification | p-Ser9 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Optimal working dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Glycogen synthase kinase 3 B glycogen synthase kinase3 beta GSK3B glycogen synthase kinase 3 beta Glycogen synthase kinase3 B Glycogen synthase kinase 3 B (phospho S9) Glycogen synthase kinase 3 B (phospho Ser9) Glycogen synthase kinase 3 B (pS9) G |
|---|---|
| Target | GSK3 beta (phospho Ser9) |
| Molecular Weight(MW) | 46 (note) |
Application
Western blot of rat cortex lysate showing phospho-specific immunolabeling of the ~46k GSK3p protein phosphorylated at Ser 9 using Glycogen synthase kinase 3 B (GSK3B) (phospho Ser9) antibody .| Application Notes | Optimal working dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For long-term storage, aliquot and store at -20 C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
