Application
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using GSK3 beta (Phospho-Ser9) Antibody. The picture on the right is treated with the synthesized peptide.Application
Western blot analysis of extracts from HeLa cells treated with EGF, using GSK3 beta (Phospho-Ser9) Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | GSK3 beta (phospho Ser9) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to GSK3 beta (phospho Ser9)Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GSK3 beta around the phosphorylation site of Ser9. |
| Modification | p-Ser9 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIHC-PIPWB |
| IHC: 1:50~1:100 : |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Glycogen synthase kinase-3 alpha GSK3A Factor A kinase GSK3alpha kinase GSK3-alpha GSK3 alpha GSK-3 alpha Glycogen synthase kinase3 alpha GSK3 beta GSK 3 alpha kinase GSK3 alpha GSK3 beta (phospho S9) GSK3 beta (phospho Ser9) GSK3 beta (pS9) |
|---|---|
| Target | GSK3 beta |
| Molecular Weight(MW) | 46 kDa (note) |
| Tissue Specificity | GSK3 beta (Phospho-Ser9) Antibody detects endogenous levels of GSK3 beta only when phosphorylated at serine9. |
Application
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using GSK3 beta (Phospho-Ser9) Antibody. The picture on the right is treated with the synthesized peptide.
Application
Western blot analysis of extracts from HeLa cells treated with EGF, using GSK3 beta (Phospho-Ser9) Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | IHC: 1:50~1:100 : |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
