Rabbit polyclonal antibody to GSK3 betaThe protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFIHC-PWB
WB: 1:500-1:1000 IHC: 1:50-1:100 IF:1:100-1:200:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
glycogen synthase kinase 3 beta GSK3B
Target
GSK3 beta
Application
Application
IHC-P analysis of human breast carcinoma tissue using GSK3 beta antibody.
Application
Confocal IF analysis of HeLa cells using GSK3 beta antibody.
Application
WB analysis of A2780 and HT29 lysates using GSK3 beta antibody.
Application Notes
WB: 1:500-1:1000 IHC: 1:50-1:100 IF:1:100-1:200:
Additional Information
Form
Liquid
Storage Instructions
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Storage Buffer
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.