Rabbit polyclonal antibody to HAT-2Histone acetyltransferases (HATs) have been implicated in a number of cellular functions including gene regulation, DNA synthesis, and repair. Histone acetyltransferases and deacetylases are, respectively, the enzymes devoted to the addition and removal of acetyl groups from lysine residues on the histone N-terminal tails. The enzymes exert fundamental roles in developmental processes and their deregulation has been linked to the progression of diverse human disorders, including cancer.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~65 kDa HAT-2 from human samples, and in a lesser extent, from mouse and rat samples. Jurkat cell lysate can be used as a positive control.:
Species Reactivity
Human
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
HATs Anti-HAT-2 antibody HAT-2 HDACs HAT-2 Polyclonal histone acetyltransferase MYST2 HAT HAT2 antibody HAT-2 antibody HDACs HAT2 Polyclonal AntiHAT2 antibody HAT2 Anti-HAT-2 AntiHAT2 HAT 2 Anti HAT 2 HAT 2 antibody Anti HAT 2 antibody
Target
HAT-2
Tissue Specificity
This antibody is specific for HAT-2.
Application
Application
Western blot analysis of HAT-2 expressionin Jurkat cell lysate
Application Notes
Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~65 kDa HAT-2 from human samples, and in a lesser extent, from mouse and rat samples. Jurkat cell lysate can be used as a positive control.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.