Rabbit Polyclonal antibody to hHR23bPlays a central role both in proteosomal degradation of misfolded proteins and DNA repair. Central component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Involved in DNA excision repair by stabilizing XPC protein. May play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage-processing enzymes.
Immunogen
The antiserum was produced against synthesized peptide derived from human RAD23B.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
RAD23B RAD23 homolog B HHR23B HR23B P58
Target
hHR23b
Molecular Weight(MW)
43 kDa (note)
Tissue Specificity
RAD23B Antibody detects endogenous levels of total RAD23B protein.
Application
Application
Western blot analysis of extracts from A549/HuvEc cells, using RAD23B Antibody. The lane on the right is treated with the synthesized peptide.
Application Notes
ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at -20 degrees Celcius. Product is stable for at least 1 year.
Storage Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.