Application
B. Immunohistochemical staining of paraffin-embedded human tonsils using anti-MHC class 1 RabMAb (cat. #).Application
A. Western blot analysis on Raji cell lysate using anti-MHC class 1 RabMAb (cat. # ) dilution 1:10000| Product Name | HLA-A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit monoclonal antibody [EP1395Y] to HLA-AThe antigenic agglomerate major histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8-positive T cells. It is now recognized that the products of the MHC genes are antigen-presenting molecules (APM) designed for the presentation of antigen fragments (peptides) to the T-cell receptor, thus participating in the immune response . Recently shown is a mechanism of antigen acquisition for cross-presentation that couples the antigen presentation system of two adjacent cells and is lost in most tumours: gap-junction-mediated intercellular peptide coupling for presentation by bystander MHC class I molecules and transfer to professional antigen presenting cells for cross-priming . The mammalian vomeronasal organ detects social information about gender, status, and individuality. It has been shown that small peptides that serve as ligands for major histocompatibility complex (MHC) class I molecules function also as sensory stimuli for a subset of vomeronasal sensory neurons located in the basal Gao- and V2R receptor-expressing zone of the vomeronasal epithelium . |
| Immunogen | A synthetic peptide corresponding to residues in human MHC class 1 was used as an immunogen. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | EP1395Y |
| Host Species | Rabbit |
| Tested Applications | ELISAFACSICC/IFIHC-FIHC-PIPWBIHC-W |
| For WB: Use at a dilution of 1:10,000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FLJ26655 HLAA HLA A A 1 alpha chain A1 alpha chain |
|---|---|
| Target | MHC class 1 |
| Molecular Weight(MW) | 41 (note) |
Application
B. Immunohistochemical staining of paraffin-embedded human tonsils using anti-MHC class 1 RabMAb (cat. #).
Application
A. Western blot analysis on Raji cell lysate using anti-MHC class 1 RabMAb (cat. # ) dilution 1:10000| Application Notes | For WB: Use at a dilution of 1:10,000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 °C. Stable for 12 months from date of receipt. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
