Rabbit polyclonal antibody to HLA-G (major histocompatibility complex, class I, G)HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human HLA-G. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MHC-G antibody HLA-G antibody "HLA class I histocompatibility antigen alpha chain G antibody" b2 microglobulin antibody HLA G antigen antibody "HLA-G histocompatibility antigen class I G antibody" HLA class I molecule antibody MHC class I antigen
Target
HLA-G
Molecular Weight(MW)
38 kDa (note)
Cellular Localization
Membrane; Single-pass type I membrane protein
Application
Application
Sample (30 ug of whole cell lysate) A: Molt-4 10% SDS PAGE diluted at 1:500
Positive Control
A431 , Molt-4 , Raji
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.