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HMGCS2 antibody, C-term

Catalog Number:OM257225
OM257225
Discount Price
OM257225-100ul
1~2 Week
100ul
OM257225-50ul
50ul
OM257225-20ul
20ul
1~2 Week
Product Profile
Product Name HMGCS2 antibody, C-term
Antibody Type Primary Antibodies
Product description Rabbit polyclonal to HMGCS2 (C-term)The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen KLH conjugated synthetic peptide between 479~508 amino acids from the C-terminal region of human HMGCS2.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications FACSIHC-PWB
ELISA: Use at 1:1,000:
Species Reactivity Human
Concentration 0.2mg/ml
Target Information
Gene Synonyms HMGCoA synthase
Hydroxymethylglutaryl-CoA synthase
mitochondrial
HydroxymethylglutarylCoA synthase
mitochondrial
3-hydroxy-3-methylglutaryl coenzyme A synthase
HMG-CoA synthase
3hydroxy3methylglutaryl coenzyme A synthase
HMGCS2
HMG CoA synthase
Target HMGCS2
Molecular Weight(MW) 56.635 kDa (note)
Application

Application

HMGCS2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application

HMGCS2 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the HMGCS2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

Western blot analysis of HMGCS2 Antibody (C-term) in HepG2 cell line lysates (35ug/lane). HMGCS2 (arrow) was detected using the purified Pab.
Application Notes ELISA: Use at 1:1,000:
Additional Information
Form Liquid
Storage Instructions Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.09% (W/V) sodium azide
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