Rabbit polyclonal antibody to ICAM5 (intercellular adhesion molecule 5, telencephalin)The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human ICAM5. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Reactivity
Human, Mouse, Rat, Rabbit, BovineHuman (100%), Mouse (81%), Rat (82%), Rabbit (82%), Bovine (85%)