Rabbit Polyclonal antibody to IGFBP2 (insulin-like growth factor binding protein 2, 36kDa)Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Immunogen
Recombinant protein encompassing a sequence within the center region of human IGFBP2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Pig, Sheep, BovineMouse (94%), Rat (95%), Pig (99%), Sheep (97%), Bovine (99%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
IBP2 antibody, IGF-BP53 antibody, IGFBP2 antibody, IGFBP-2 antibody, IBP-2 antibody, insulin-like growth factor-binding protein 2 antibody, IGF-binding protein 2 antibody, "insulin-like growth factor binding protein 2, 36kDa antibody"
Molecular Weight(MW)
35 kDa (note) (5)
Cellular Localization
Secreted
Application
Application
Immunohistochemical analysis of paraffin-embedded human breast cancer, using IGFBP2 antibody at 1:250 dilution.
Application
Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE diluted at 1:1000
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.