Rabbit polyclonal antibody to IL1R1 (interleukin 1 receptor, type I)The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human IL1 Receptor 1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, BovineMouse (81%), Bovine (83%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
CD121A antibody D2S1473 antibody IL-1R-alpha antibody IL1R antibody IL1RA antibody P80 antibody IL1R1 antibody IL-1R-1 antibody interleukin-1 receptor alpha antibody "interleukin 1 receptor alpha type I antibody" CD121 antigen-like family member
Target
IL1R1
Molecular Weight(MW)
65 kDa (note) (8)
Cellular Localization
Membrane; Single-pass type I membrane protein
Application
Application
Sample (30 ug of whole cell lysate) A: Molt-4 7.5% SDS PAGE diluted at 1:5000
Positive Control
Molt-4 , *LNCaP
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.