Rabbit polyclonal antibody to IL5The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant human IL5
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAFACSIHC-PWBFunctional Assay
ELISA: 0.5 - 2.0 ug/ml:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
EDF TRF IL-5
Target
Interleukin-5
Tissue Specificity
This antibody recognizes human IL5 (Interleukin-5).
Application
Application
IHC-P ImageStaining of formalin fixed, paraffin embedded human colo-rectal carcinoma with Rabbit anti Human interleukin-5
Application Notes
ELISA: 0.5 - 2.0 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
Prior to reconstitution store at +4°C. After reconstitution store at -20°C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.