Application
Immunofluorescence analysis of methanol-fixed A431, using Inhibin beta B antibody at 1:200 dilution.Application
Sample (30 µg of whole cell lysate) A: A431 B: H1299 10% SDS PAGE diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.Application
Inhibin beta B antibody [C3], C-term detects Inhibin beta B protein at cytoplasm on human normal kidney by immunohistochemical analysis. Sample: Paraffin-embedded human normal kidney. Inhibin beta B antibody [C3], C-term diluted at 1:500.| Product Name | Inhibin beta B antibody , C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Inhibin beta B (inhibin, beta B)The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Inhibin beta B. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Zebrafish, Pig, Chicken, BovineMouse (100%), Rat (100%), Zebrafish (100%), Pig (100%), Chicken (100%), Bovine (100%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | MGC157939 antibody INHBB antibody activin beta-B chain antibody "Inhibin beta-2 antibody" activin AB beta polypeptide antibody inhibin beta B chain antibody "inhibin beta B antibody" |
|---|---|
| Molecular Weight(MW) | 45 kDa (note) |
Application
Immunofluorescence analysis of methanol-fixed A431, using Inhibin beta B antibody at 1:200 dilution.
Application
Sample (30 µg of whole cell lysate) A: A431 B: H1299 10% SDS PAGE diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Application
Inhibin beta B antibody [C3], C-term detects Inhibin beta B protein at cytoplasm on human normal kidney by immunohistochemical analysis. Sample: Paraffin-embedded human normal kidney. Inhibin beta B antibody [C3], C-term diluted at 1:500.| Positive Control | A431 , H1299 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
