| Product Name | Integrin alpha 2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Monoclonal antibody [EPR5788] to Integrin alpha 2This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
| Immunogen | Synthetic peptide corresponding to residues in the extracellular domain of human Integrin alpha 2. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | EPR5788 |
| Host Species | Rabbit |
| Tested Applications | FACSIHC-PWB |
| Flow Cyt: 1/10 - 1/1000. WB: 1/10000 - 1/50000. Detects a band of approximately 150 kDa. Is unsuitable for ICC/IF. IHC-P: 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | HPA-5 CD49B VLAA2 VLA-2 ITGA2 integrin alpha 2 (CD49B alpha 2 subunit of VLA-2 receptor) BR GPIa |
|---|---|
| Target | Integrin alpha 2 |
| Molecular Weight(MW) | 129 kDa (note) |
| Application Notes | Flow Cyt: 1/10 - 1/1000. WB: 1/10000 - 1/50000. Detects a band of approximately 150 kDa. Is unsuitable for ICC/IF. IHC-P: 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C. Stable for 12 months at -20°C |
| Storage Buffer | pH: 7.4, Preservative: 0.01% Sodium azide. Constituents: 50% Glycerol, 0.05% BSA |
