Application
Western blot analysis of extracts from NIH-3T3 cells, treated with etoposide 25uM 24h, using ITGA5 (heavy chain,Cleaved-Phe42) Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | Integrin alpha 5 (cleaved Phe42) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Integrin alpha 5 (cleaved Phe42)Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ITGA5. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ITGA5 VLA5A CD49e FNRA ITGA5 (cleaved F42) ITGA5 (cleaved Phe42) ITGA5 cleaved F42 ITGA5 cleaved Phe42 Cleaved ITGA5 (F42) Cleaved ITGA5 (Phe42) |
|---|---|
| Target | Integrin alpha 5 (cleaved Phe42) |
| Molecular Weight(MW) | 92 kDa (note) |
| Tissue Specificity | ITGA5 (heavy chain,Cleaved-Phe42) Antibody detects endogenous levels of fragment of activated ITGA5 resulting from cleavage adjacent to Phe42. |
Application
Western blot analysis of extracts from NIH-3T3 cells, treated with etoposide 25uM 24h, using ITGA5 (heavy chain,Cleaved-Phe42) Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
