Application
Western blot analysis of extracts from HL60 and HT29 cells using Integrin beta 3 Antibody .Application
Western blot analysis of extracts from HL60 and HT29 cells using Integrin b3(Ab-785) Antibody| Product Name | Integrin beta 3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Integrin beta 3The Itg-Beta3 gene encodes the beta subunit of the platelet membrane adhesive protein receptor complex Itg-Beta3 protein, which belongs to the Integrin class of cell adhesion molecule receptors that share a common heterotrimeric structure with Alpha and Beta subunits. It is a common Beta subunit of the platelet complex and of two other Integrins (Fibronectin and Vitronectin Receptors), which have distinct Alpha subunits. Itg-Beta3 has been implicated in a wide variety of functions, including platelet aggregation and thrombosis and implantation, placentation, angiogenesis, bone remodeling, and tumor progression. Glanzmann Thrombasthenia can result from defects in the genes for either the Itg-Alpha2B or the Itg-Beta3 subunit |
| Immunogen | Peptide sequence around aa.783~787 (I-T-Y-R-G) derived from Human Integrin B3/ITGB3. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.: |
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CD61 GP3A GPIIIa ITGB3 integrin beta-3 platelet glycoprotein IIIa platelet membrane glycoprotein IIIa integrin beta 3 (platelet glycoprotein IIIa antigen CD61) |
|---|---|
| Target | Integrin beta 3 |
| Molecular Weight(MW) | 110 (note) |
Application
Western blot analysis of extracts from HL60 and HT29 cells using Integrin beta 3 Antibody .
Application
Western blot analysis of extracts from HL60 and HT29 cells using Integrin b3(Ab-785) Antibody| Application Notes | Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
