Application
Immunohistochemistry of IRF7 in mouse spleen tissue with IRF7 antibody at 5 ug/ml.Application
Western blot analysis of IRF7 in 293 whole cell lysate with IRF7 antibody at (A) 0.5 and (B) 1 ug/ml.| Product Name | IRF7 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to IRF7Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling (3,4). There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Interferon regulatory factor 7 Interferon regulatory factor7 IRF7 |
|---|---|
| Target | IRF7 |
| Tissue Specificity | This antibody is specific for IRF7 Internal |
Application
Immunohistochemistry of IRF7 in mouse spleen tissue with IRF7 antibody at 5 ug/ml.
Application
Western blot analysis of IRF7 in 293 whole cell lysate with IRF7 antibody at (A) 0.5 and (B) 1 ug/ml.| Positive Control | Blocking Peptide: Cat.No. GTX85489-PEP - IRF7 Peptide Lysates: Cat. No. GTX27902 - 293 Cell Lysate |
|---|---|
| Application Notes | IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
