Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Jak2 (Ab-570) Antibody (left) or the same antibody preincubated with blocking peptide (right)
Rabbit polyclonal antibody to JAK2This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]
Immunogen
Peptide sequence around aa.568~572 (G-D-Y-G-Q) derived from Human JAK2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHC-P
Suggested starting dilutions are as follows. IHC-P: 1:50~1:100. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Species Reactivity
HumanRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
THCYT3 JTK10
Target
Jak2
Molecular Weight(MW)
125 (note)
Application
Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Jak2 (Ab-570) Antibody (left) or the same antibody preincubated with blocking peptide (right)
Application Notes
Suggested starting dilutions are as follows. IHC-P: 1:50~1:100. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.