| Product Name | JLP antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to JLPExtracellular signals are transduced into cells through mitogen-activated protein kinases. The structural organization of these kinases into specific signaling domains is facilitated by scaffolding proteins involved in closely tethering different kinases so that successive phosphorylation events can occur. The protein encoded by this gene is a scaffolding protein that brings together mitogen-activated protein kinases and their transcription factor targets for the activation of specific signaling pathways. This gene which is abundantly expressed in testicular haploid germ cells encodes a protein that is recognized by sperm-agglutinating antibodies and implicated in infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| Western blotting (1:500-1:2500) and Immunoprecipitation. HeLa nuclear extract can be used as a positive control. However, the optimal concentrations should be determined individually. The antibody recognizes the JLP of human and mouse origins. Reactivity to other species has not been tested.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | JNKassociated leucine zipper protein1 JNKassociated leucine zipper protein 1 SPAG9 JLP-1 JLP JLP1 JNK-associated leucine zipper protein 1 JLP 1 |
|---|---|
| Target | JLP |
| Tissue Specificity | This antibody is specific for JLP. |
| Cellular Localization | Perinuclear distribution in response to stress signals such as UV radiation. Associated with the plasma membrane of the acrosomal compartment and also localizes in the acrosome matrix. |
| Application Notes | Western blotting (1:500-1:2500) and Immunoprecipitation. HeLa nuclear extract can be used as a positive control. However, the optimal concentrations should be determined individually. The antibody recognizes the JLP of human and mouse origins. Reactivity to other species has not been tested.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Stored at -20 °C for future use. |
| Storage Buffer | PBS (pH 7.2) containing 30% glycerol, 1% BSA and 0.02% thimerosal |
