Rabbit polyclonal antibody to Kappa Opioid receptorOpioid is the term used to designate a group of compounds that are opium-like in their properties. These drugs have effects on perception of pain, consciousness, motor control, mood, and autonomic function, and can induce physical dependence. Pharmacological studies suggested that there are at least 3 major classes of opioid receptors, designated delta, kappa, and mu. They differ in their affinity for various opioid ligands and in their cellular distribution. Studies of the receptors in the mouse and rat show that they are structurally related and are members of the family of 7 transmembrane-spanning G protein-coupled receptors. The kappa opiod receptor inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for beta-endorphin.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
We recommend the following starting dilutions: ELISA 1:1000-1:5000, Western Blot 1:500-1:1000,. Optimal concentration should be determined experimentally by the end user.:
Species Reactivity
HumanMouseMonkeyRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
KOR-1 (R361) detects endogenous levels of KOR-1 protein.
Application
Application
Western Blot: KOR-1 Antibody [ - Western blot (WB) analysis of KOR-1 (R361) antibody in extracts from COS-7 cells.
Application Notes
We recommend the following starting dilutions: ELISA 1:1000-1:5000, Western Blot 1:500-1:1000,. Optimal concentration should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.