Application
Sample (30 ug of whole cell lysate) A: Hela B: JurKat 7.5% SDS PAGE diluted at 1:1000| Product Name | K-cadherin antibody , Internal |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to K-cadherin (cadherin 6, type 2, K-cadherin (fetal kidney))This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human K-cadherin. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Chicken, BovineMouse (97%), Rat (96%), Chicken (82%), Bovine (97%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | KCAD antibody CDH6 antibody cadherin-6 antibody "cadherin 6 type 2 K-cadherin (fetal kidney) antibody" |
|---|---|
| Target | K-cadherin |
| Molecular Weight(MW) | 88 kDa (note) |
| Cellular Localization | Cell membrane |
Application
Sample (30 ug of whole cell lysate) A: Hela B: JurKat 7.5% SDS PAGE diluted at 1:1000| Positive Control | HeLa , Jurkat , NT2D1 |
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| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
