Rabbit polyclonal antibody to KCC4 (solute carrier family 12 (potassium/chloride transporters), member 7)Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification.
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human KCC4. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
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Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Rabbit, ChickenMouse (92%), Rat (91%), Rabbit (86%), Chicken (81%)