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KCNH6 antibody
Catalog Number:OM260385
OM260385
Discount Price
OM260385-100ul
1~2 Week
100ul
OM260385-50ul
50ul
OM260385-20ul
20ul
1~2 Week
Product Profile
Product Name KCNH6 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to KCNH6Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
Immunogen Peptide TLNFVEFNLEKHRS(C), corresponding to amino acid residues 185-198 of human Kv11.2 (Accession Q9H252). Intracellular, N-terminal part.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
IHC:1:50~1:200
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms Kv11.2
HERG2
potassium voltage-gated channel
subfamily H (eag-related)
member 6
ERG2
Target KCNH6
Application

Application

Anti-KV11.2_(erg2) - Western blot analysis of rat brain (1 and 3) and rat cortex ( 2 and 4) lysate: 1, 2. Anti-Kv11.2 (erg2) antibody, (1:200). 3, 4. Anti-Kv11.2 (erg2) antibody, preincubated with the control peptide antigen.

Application

Anti-KV11.2_(erg2) - Expression of KV11.2 in rat hippocampus Immunohistochemical staining of Kv11.2 in rat hippocampus using Anti-Kv11.2 (erg2) antibody. A. Kv11.2 appears as diffuse staining (green) that defines the boundary of the reticular nucleus of thalamus (arrow). B. Staining with mouse anti-parvalbumin (PV, red) demonstrates both neuronal and diffuse staining. C. Confocal merge of KV11.2 and PV demonstrates overlap of the two markers labeling the reticular nucleus of the thalamus (orange).
Application Notes IHC:1:50~1:200
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.025% NaN3.
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