Western blot analysis of extracts from K562 cells treated with TNF using Phospho-Kv2.1 (Ser805) antibody. The lane on the right is treated with the antigen-specific peptide.
Rabbit Polyclonal antibody to Kv2.1 (phospho Ser805)Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]
Immunogen
Peptide sequence around phosphorylation site of serine805(P-T-S(p)-P-K) derived from Human Kv2.1 .
Modification
p-Ser805
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
KV2.1 EIEE26 potassium channel voltage gated Shab related subfamily B member 1 KCNB1 h-DRK1 DRK1
Target
Kv2.1 (phospho Ser805)
Tissue Specificity
The antibody detects endogenous level of Kv2.1 only when phosphorylated at serine 805.
Application
Application
Western blot analysis of extracts from K562 cells treated with TNF using Phospho-Kv2.1 (Ser805) antibody. The lane on the right is treated with the antigen-specific peptide.
Application Notes
WB: 1:500 - 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20˚C/1 year
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.