Application
Western blot analysis of extracts of HeLa cell line, using LMNB1 antibody.| Product Name | Lamin B1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Lamin B1The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010] |
| Immunogen | Recombinant protein of human LMNB1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | FACSICC/IFIHC-PIPWB |
| WB 1:500 - 1:1000, IHC 1:50 - 1:100, IF 1:20 - 1:50, IP 1:20 - 1:50, FACS 1:20 - 1:50: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | LMN2 LMN LMNB1 ADLD LMNB lamin B1 |
|---|---|
| Target | Lamin B1 |
| Molecular Weight(MW) | 66 kDa (note) |
Application
Western blot analysis of extracts of HeLa cell line, using LMNB1 antibody.| Application Notes | WB 1:500 - 1:1000, IHC 1:50 - 1:100, IF 1:20 - 1:50, IP 1:20 - 1:50, FACS 1:20 - 1:50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
