Application
IHC-P analysis of rat brain tissue using LDLR antibody.Application
WB analysis of rat brain lysate using LDLR antibody.Application
IHC-P analysis of human rectal carcinoma using LDLR antibody.Application
IHC-P analysis of rat brain tissue using LDLR antibody at a dilution of 1:200.| Product Name | LDL Receptor antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to LDL ReceptorThe low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010] |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml): |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | low density lipoprotein receptor LDLR FHC LDLCQ2 FH |
|---|---|
| Target | LDL Receptor |
Application
IHC-P analysis of rat brain tissue using LDLR antibody.
Application
WB analysis of rat brain lysate using LDLR antibody.
Application
IHC-P analysis of human rectal carcinoma using LDLR antibody.
Application
IHC-P analysis of rat brain tissue using LDLR antibody at a dilution of 1:200.| Application Notes | P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
| Storage Buffer | 10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide |
