Rabbit polyclonal antibody to LeptinThis gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
WB:1:100~1:200 IHC:1:10~1:50 ELISA:1:1000~5000
Species Reactivity
HumanMousePigRatSheep
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
leptin LEPD LEP OB OBS
Target
Leptin
Application
Application
IHC-P analysis of rat brain tissue using Leptin antibody.
Application
IHC-P analysis of human gaster tissue using Leptin antibody.
Application Notes
WB:1:100~1:200 IHC:1:10~1:50 ELISA:1:1000~5000
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Storage Buffer
10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide