Application
Western blot analysis of extracts of various cell lines, using LEPR antibody.Application
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using LEPR antibody.Application
Immunohistochemistry of paraffin-embedded rat lung using LEPR antibody at dilution of 1:200 (400x lens).Application
Immunohistochemistry of paraffin-embedded mouse kidney using LEPR antibody at dilution of 1:200 (400x lens).| Product Name | Leptin receptor antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Leptin receptorThe protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010] |
| Immunogen | A synthetic peptide of human LEPR |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIHC-PWB |
| WB 1:500 - 1:1000, IHC 1:50 - 1:100: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CD295 LEP-R OB-R leptin receptor LEPR LEPRD OBR |
|---|---|
| Target | Leptin receptor |
| Molecular Weight(MW) | 96 kDa (note) |
Application
Western blot analysis of extracts of various cell lines, using LEPR antibody.
Application
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using LEPR antibody.
Application
Immunohistochemistry of paraffin-embedded rat lung using LEPR antibody at dilution of 1:200 (400x lens).
Application
Immunohistochemistry of paraffin-embedded mouse kidney using LEPR antibody at dilution of 1:200 (400x lens).| Application Notes | WB 1:500 - 1:1000, IHC 1:50 - 1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
