Rabbit Polyclonal antibody to LRRN2 (leucine rich repeat neuronal 2)The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human LRRN2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, RatMouse (93%), Rat (94%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
FIGLER7 antibody, GAC1 antibody, LRANK1 antibody, LRRN5 antibody, LRRN2 antibody, leucine rich repeat neuronal 5 antibody, leucine rich and ankyrin repeats 1 antibody, "fibronectin type III, immunoglobulin and leucine rich repeat domain 7 antibody", leucin
Molecular Weight(MW)
79 kDa (note) (2)
Cellular Localization
Membrane; Single-pass type I membrane protein
Application
Application
Immunohistochemical analysis of paraffin-embedded human hepatoma, using LRRN2 antibody at 1:500 dilution.
Application
Sample (30 ug of whole cell lysate) A: U87-MG 7.5% SDS PAGE diluted at 1:1000
Positive Control
U87-MG
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.