Rabbit polyclonal antibody to lymphotoxin alpha (lymphotoxin alpha (TNF superfamily, member 1))Lymphotoxin alpha, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. LTA is highly inducible, secreted, and exists as homotrimeric molecule. LTA forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. LTA is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human lymphotoxin alpha. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Reactivity
Human, Mouse, Rat, Dog, Rabbit, Rhesus Monkey, ChimpanzeeHuman (100%), Mouse (81%), Rat (81%), Dog (83%), Rabbit (81%), Rhesus Monkey (98%), Chimpanzee (100%)