Rabbit polyclonal antibody to MANBA (mannosidase, beta A, lysosomal)This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human MANBA. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
MANB1 antibody, MANBA antibody, lysosomal beta A mannosidase antibody, mannase antibody, beta-mannosidase antibody, mannanase antibody, "mannosidase, beta A, lysosomal antibody"
Target
MANBA
Molecular Weight(MW)
101 kDa (note)
Cellular Localization
Lysosome
Application
Application
Sample(30 μg of whole cell lysate) A:Hep G2 7.5% SDS PAGE diluted at 1:500
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.