Application
Western blot analysis of extracts of various cell lines, using MBTPS1 antibody.Application
Immunohistochemistry of paraffin-embedded Human liver injury using MBTPS1 antibody at dilution of 1:100 (x400 lens).Application
Immunofluorescence analysis of U20S cell using MBTPS1 antibody. Blue: DAPI for nuclear staining.| Product Name | MBTPS1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to MBTPS1The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant protein of human MBTPS1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-PWB |
| WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:100: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PCSK8 membrane-bound transcription factor peptidase site 1 SKI-1 S1P |
|---|---|
| Target | MBTPS1 |
| Molecular Weight(MW) | 118 kDa (note) |
Application
Western blot analysis of extracts of various cell lines, using MBTPS1 antibody.
Application
Immunohistochemistry of paraffin-embedded Human liver injury using MBTPS1 antibody at dilution of 1:100 (x400 lens).
Application
Immunofluorescence analysis of U20S cell using MBTPS1 antibody. Blue: DAPI for nuclear staining.| Application Notes | WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
