Rabbit Polyclonal antibody to MCH-1RThe protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin. [provided by RefSeq, Jul 2008]
Immunogen
MCHR1 antibody was raised against synthetic 20 amino acid peptide from N-terminal extracellular domain of human MCHR1. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey (100%); Mouse (85%).