Rabbit Polyclonal antibody to MEK1/2The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]
Immunogen
A synthesized peptide derived from human MEK1/2
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
WB 1:500-1:2000, IHC 1:50-1:200:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
PRKMK1 MKK1 MAP2K1 mitogen-activated protein kinase kinase 1 MAPKK1 MEK1
Target
MEK1/2
Tissue Specificity
MAP2K1
Application
Application
Western blot analysis of MEK1/2 expression in UV treated Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Application Notes
WB 1:500-1:2000, IHC 1:50-1:200:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.