Rabbit Polyclonal antibody to Methyl CpG Binding Protein 2DNA methyltransferases methylate the 5-position of cytosine in the context of CpG dinucleotides. DNA methylation is crucial for normal embryonic development, imprinting, and X-chromosome inactivation. Methyl CpG binding proteins (MeCPs) specifically recognize methylated regions of DNA and repress transcription both directly and by association with known corepressor proteins which include members of the Sin3 and histone deactylase protein families.
Immunogen
Synthetic Peptide: M(1) V A G M L G L R E E K S E D(15) C
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ICC/IFIHCIHC-PIPWB
IHC-P: 1:200 - 1:2000:
Species Reactivity
HumanMouseRatAmphibiansPrimate
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)