Application
Immunocytochemistry/Immunofluorescence: metabotropic Glutamate Receptor 3 Antibody [ - Cells expressing vector only immunostained with target antibody. Untransfected HEK293 human embryonic kidney cells.Application
Immunocytochemistry/Immunofluorescence: metabotropic Glutamate Receptor 3 Antibody [ - Cells expressing target protein immunostained with target antibody. Staining of transfected HEK293 human embryonic kidney cells.Application
Immunohistochemistry: mGluR3 antibody [ - Staining of neurons and glial cells in paraffin-embedded brain sections.| Product Name | mGluR3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Metabotropic Glutamate receptor 3The Metabotropic Glutamate Receptor GRM3 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Metabotropic glutamate receptor Group II includes the GRM2 and GRM3 receptors that are linked to inhibition of the cyclic AMP signaling cascade. GRM3 has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain, embryo, fetal lung/testis/B-cell, nerve, placenta, prostate, and vessel libraries. Caution: GLUR3 refers to Ionotropic Glutamate Receptor 3, not to Metabotropic Glutamate Receptor 3 (mGLUR3). |
| Immunogen | The immunogen corresponding to a region within amino acid 425 and 475 of Metabotropic Glutamate Receptor 3 (NP_000831.2). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-FIHC-PWB |
| We recommend the following starting dilutions: immunohistochemistry 3 ug/ml to 17 ug/ml, Western Blot 3 ug/ml to 17 ug/ml, Immunocytochemistry 3 ug/ml to 17 ug/ml, Immunohistochemistry-Paraffin 3 ug/ml to 17 ug/ml, Immunohistochemistry-Frozen 3 ug/ml to 17 ug/ml. Optimal concentration should be determined experimentally by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | mGlu 3 Metabotropic glutamate receptor 3 GLUR3 Glutamate receptor metabotropic 3 GLUR 3 MGLUR 3 2913 Metabotropic glutamate receptor3 precursor a MGlu3 MGLUR3 GRM 3 Glutamate receptor metabotropic3 GRM3 GPRC1C Metabotropic glutamate receptor3 |
|---|---|
| Target | Metabotropic Glutamate receptor 3 |
| Tissue Specificity | Metabotropic Glutamate Receptor 3 |
Application
Immunocytochemistry/Immunofluorescence: metabotropic Glutamate Receptor 3 Antibody [ - Cells expressing vector only immunostained with target antibody. Untransfected HEK293 human embryonic kidney cells.
Application
Immunocytochemistry/Immunofluorescence: metabotropic Glutamate Receptor 3 Antibody [ - Cells expressing target protein immunostained with target antibody. Staining of transfected HEK293 human embryonic kidney cells.
Application
Immunohistochemistry: mGluR3 antibody [ - Staining of neurons and glial cells in paraffin-embedded brain sections.| Application Notes | We recommend the following starting dilutions: immunohistochemistry 3 ug/ml to 17 ug/ml, Western Blot 3 ug/ml to 17 ug/ml, Immunocytochemistry 3 ug/ml to 17 ug/ml, Immunohistochemistry-Paraffin 3 ug/ml to 17 ug/ml, Immunohistochemistry-Frozen 3 ug/ml to 17 ug/ml. Optimal concentration should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline, PH 7.7 |
