Application
WB analysis of extracts from various cell lines using mGluR3 antibody.Application
IHC-P analysis of human lung cancer using mGluR3 antibody at a dilution of 1:200.Application
IHC-P analysis of human liver cancer using mGluR3 antibody at a dilution of 1:200.Application
ICC/IF analysis of U2OS cells using mGluR3 antibody (green) and DAPI (blue).| Product Name | mGluR3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to mGluR3L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant protein of human GRM3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| WB: 1:500 - 1:200. IHC: 1:50 - 1:20. IF: 1:50 - 1:200: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | GRM3 glutamate receptor metabotropic 3 GPRC1C mGlu3 GLUR3 MGLUR3 |
|---|---|
| Target | mGluR3 |
| Molecular Weight(MW) | 98 kDa (note) |
Application
WB analysis of extracts from various cell lines using mGluR3 antibody.
Application
IHC-P analysis of human lung cancer using mGluR3 antibody at a dilution of 1:200.
Application
IHC-P analysis of human liver cancer using mGluR3 antibody at a dilution of 1:200.
Application
ICC/IF analysis of U2OS cells using mGluR3 antibody (green) and DAPI (blue).| Application Notes | WB: 1:500 - 1:200. IHC: 1:50 - 1:20. IF: 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
