Application
MGST1 antibody [N1C3] detects MGST1 protein at cytoplasm in mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. MGST1 antibody [N1C3] diluted at 1:500.Application
MGST1 antibody [N1C3] detects MGST1 protein at cytoplasm in rat liver by immunohistochemical analysis. Sample: Paraffin-embedded rat liver. MGST1 antibody [N1C3] diluted at 1:500.| Product Name | MGST1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to MGST1 (microsomal glutathione S-transferase 1)The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Four transcript variants of this gene encode one protein isoform. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human MGST1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanMouseRat |
| Predicted Reactivity | Pig, Chimpanzee, BovinePig (89%), Chimpanzee (99%), Bovine (87%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MGST GST12 microsomal glutathione S-transferase 1 MGST-I |
|---|---|
| Target | MGST1 |
| Molecular Weight(MW) | 18 kDa (note) (6) |
| Cellular Localization | Microsome (By similarity) , Mitochondrion outer membrane; Peripheral membrane protein (By similarity) , Endoplasmic reticulum |
Application
MGST1 antibody [N1C3] detects MGST1 protein at cytoplasm in mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. MGST1 antibody [N1C3] diluted at 1:500.
Application
MGST1 antibody [N1C3] detects MGST1 protein at cytoplasm in rat liver by immunohistochemical analysis. Sample: Paraffin-embedded rat liver. MGST1 antibody [N1C3] diluted at 1:500.| Positive Control | HeLa , HepG2 , Mouse liver , Rat liver |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
