Rabbit Polyclonal antibody to MicrocephalinThis gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
Immunogen
Recombinant protein of human MCPH1
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB 1:500 - 1:2000, IHC 1:50 - 1:200:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
microcephalin 1 MCT BRIT1 MCPH1
Target
Microcephalin
Molecular Weight(MW)
93 kDa (note)
Application
Application
Western blot analysis of extracts of various cell lines, using MCPH1 antibody.