Application
WB analysis of () rat brain and (2) rat kidney lysates using MR antibody at a dilution of 1:200.| Product Name | Mineralocorticoid Receptor antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Mineralocorticoid ReceptorThis gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml): |
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| Species Reactivity | HumanMouseChickenDogPigRatBovine |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | NR3C2 NR3C2VIT nuclear receptor subfamily 3 group C member 2 MLR MCR MR |
|---|---|
| Target | Mineralocorticoid Receptor |
Application
WB analysis of () rat brain and (2) rat kidney lysates using MR antibody at a dilution of 1:200.| Application Notes | P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
| Storage Buffer | 10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide. |
