Application
IHC-P analysis of human kidney tissue using Mineralocorticoid Receptor antibody at 4.0-8.0μg/ml.Application
WB analysis of A172 cells using Mineralocorticoid Receptor antibody at 1.25μg/ml.| Product Name | Mineralocorticoid Receptor antibody, Internal |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Mineralocorticoid ReceptorThis gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
| Immunogen | A synthetic peptide corresponding to an Internal region of Human Mineralocorticoid Receptor |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Cow: 83%; Guinea Pig: 75%; Horse: 86%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 100%; Rat: 92% |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | MR MCR NR3C2 MLR NR3C2VIT |
|---|---|
| Target | Mineralocorticoid Receptor |
| Molecular Weight(MW) | 107 KDa (note) |
Application
IHC-P analysis of human kidney tissue using Mineralocorticoid Receptor antibody at 4.0-8.0μg/ml.
Application
WB analysis of A172 cells using Mineralocorticoid Receptor antibody at 1.25μg/ml.| Positive Control | A172 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
