Application
Western blot analysis of extracts from A549 cells, treated with etoposide 25uM 1h, using MMP17 (Cleaved-Gln129) Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | MMP17 (cleaved Gln129) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to MMP17 (cleaved Gln129)Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MMP17. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | EC3.4.24. MT4-MMP matrix metalloproteinase-17 EC 3.4.24. EC 3.4.24.- MMP-17 MT4MMP MTMMP 4 matrix metalloproteinase17 MMP17 MTMMP4 MT-MMP 4 MMP 17 MT4 MMP MT MMP 4 matrix metalloproteinase 17 MMP17 (cleaved Q129) MMP17 (cleaved Gln129) MM |
|---|---|
| Target | MMP17 |
| Molecular Weight(MW) | 53 kDa (note) |
| Tissue Specificity | MMP17 (Cleaved-Gln129) Antibody detects endogenous levels of fragment of activated MMP17 resulting from cleavage adjacent to Gln129. |
Application
Western blot analysis of extracts from A549 cells, treated with etoposide 25uM 1h, using MMP17 (Cleaved-Gln129) Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
