Application
Application| Product Name | MMP2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to MMP2The mammalian matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes (ref 1). After cleavage of a signal peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N-terminal propeptide domain is cleaved to generate the active forms of MMP (ref 2). MMP-2 (72 kDa type IV collagenase, Gelatinase-A) contain the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling. |
| Immunogen | E. coli-expressed active rat 72-kDa type IV collagenase (catalytic domain) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| For IP: Use at a dilution of 1:500. For WB: Use at a dilution of 1:2000. Optimal dilutions/concentrations should be determined by the researcher: |
|
| Species Reactivity | Rat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | TBE-1 MMP2 CLG4A P08253 CLG4 120360 MMPII 81686 4313 MMP-II MONA TBE1 TBE 1 MMP II |
|---|---|
| Target | MMP2 |
| Tissue Specificity | MMP2 - No cross-reactivity with other MMP family members. |
Application
Application| Application Notes | For IP: Use at a dilution of 1:500. For WB: Use at a dilution of 1:2000. Optimal dilutions/concentrations should be determined by the researcher: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline containing 0.1% sodium azide |
