| Product Name | MMP23 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to MMP23Matrix Metalloproteinase 23 (MMP21, MMP22, MIFR2, CAMMP) was first described in tumor cells. MMP23 shares much of the same domain structure as the classical MMPs, but has a unique cysteine array. The cysteine switch that is found in the classical MMPs is lacking or has a different sequence in MMP23. MMP23 has a furin cleavage site and it is thought to be localized within the cell. MMP23 has been reported as splice variants with different truncations at its C-terminus. MMP23 is predominantly expressed in ovary, testis, and prostate indicating that it plays a specialized role in reproductive processes. The human MMP23 gene has the chromosomal location of 1p36.3. The chromosome 1 location is a unique position among all the MMP genes currently mapped. |
| Immunogen | Synthetic peptide (Human) C-term. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-FIPWB |
| For ELISA: Use at an assay dependent dilution. For IHC-Fr: Use at an assay dependent dilution. For IP: Use at an assay dependent dilution. For WB: Use at a dilution of 1:1,000. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | 603320 O75900 MMP23B 8510 MIFR-1 Q9UBR9 MIFR MMP23A MIFR1 603321 MMP22 MMP23 8511 MMP21 MIFR 1 |
|---|---|
| Target | MMP23 |
| Tissue Specificity | reacts with reduced and non-reduced MMP-23. Recognizes the pro-form and active forms of MMP-23 as well as a series of further cleaved active forms. The hemopexin domain is removed from the smallest active form of MMP-23 and the antibody does not detect this form. |
| Application Notes | For ELISA: Use at an assay dependent dilution. For IHC-Fr: Use at an assay dependent dilution. For IP: Use at an assay dependent dilution. For WB: Use at a dilution of 1:1,000. Optimal dilutions/concentrations should be determined by the researcher.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide |
