Application
WB analysis of extracts from various cells using MMP25 antibody.Application
IHC-P analysis of Human lung cancer tissue using MMP25 antibody.Application
IHC-P analysis of human lung cancer using MMP25 antibody at a dilution of 1:200.Application
IHC-P analysis of human rectal cancer using MMP25 antibody at a dilution of 1:200.| Product Name | MMP25 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to MMP25Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred |
| Immunogen | A synthetic peptide of human MMP25 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MMP-25 MT6MMP matrix metallopeptidase 25 MT6-MMP MT-MMP 6 MMPL1 MT-MMP6 MTMMP6 MMP20A MMP20 |
|---|---|
| Target | MMP25 |
| Molecular Weight(MW) | 63 kDa (note) |
Application
WB analysis of extracts from various cells using MMP25 antibody.
Application
IHC-P analysis of Human lung cancer tissue using MMP25 antibody.
Application
IHC-P analysis of human lung cancer using MMP25 antibody at a dilution of 1:200.
Application
IHC-P analysis of human rectal cancer using MMP25 antibody at a dilution of 1:200.| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
