| Product description |
Rabbit polyclonal to MMP9The mammalian matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes (ref 1). After cleavage of a signal peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N-terminal propeptide domain is cleaved to generate the active forms of MMP (ref 2). MMP-9 (92 kDa type IV collagenase, Gelatinase-B) contain the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling. |