Application
Western blot analysis of extracts from 293/COS7/HuvEc cells, treated with IFN 2500U/ml 30', using MOL1A antibody . The lane on the right is treated with the synthesized peptide.| Product Name | MOL1A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to MOL1AActivator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MOL1A. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: 1:40000Optimal dilutions should be determined experimentally by the end user.: |
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| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Mps One Binder kinase activatorlike1A MOL1A Mps One Binder kinase activatorlike 1A MATS2 MOB1 Mps One Binder kinase activator-like 1A Molecular weight: 24959.63 |
|---|---|
| Target | MOL1A |
| Molecular Weight(MW) | 25 kDa (note) |
| Tissue Specificity | MOL1A Antibody detects endogenous levels of total MOL1A protein. |
Application
Western blot analysis of extracts from 293/COS7/HuvEc cells, treated with IFN 2500U/ml 30', using MOL1A antibody . The lane on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:40000Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
